Hey, ms, I’m still real new to Podium, too, but I might suggest something I’ve learned already. When you have MIDI in and outs all hooked up and working it can sometimes block or interfere with the audio, depending on if you are using certain ASIOs. This is not a bug, just something to be mindful of.
When I am done using MIDI, I will disconnect that stuff and check to make sure my audio is set right and then return to full audio playback. If you can post more details someone might be able to figure out what’s going on. My hunch so far is that it has to do with what audio driver(s) you use.
Someone else will know more about the issue regarding your plugins.