Well, I’ve found the cause of the noise in the 64bit engine…
My Toneport UX8 had it’s ASIO driver set to 24bit. If I change it to 32bit, it works fine, and back to 24bit, and the 64bit engine gives noise.
I’m not sure *why*, and it hasn’t affected any other hosts with 64bit engines, but I’m sure you’re more likely to offer a technical explanation than I can 
Anyway, I can live with it set to 32bit (and it’s probably better overall anyway), but let me know if you need it tested again at any time.