I guess you tried Shortcircuit v2 first. It is known to have some bugs and is abandonware now, yet never caused me any problems so far. But still.
So, I’m not very sure what might be the problem, but it is my guess that there’s something with the routing in SC itself.
Try this: Delete all the MIDI tracks from 2 to 16, and use the first one only as a master MIDI track. Then assign every sound, sample, instrument in Shocrtcircuit to its own audio output channel. This is done in the “Output” section at the right, under “Pan” – out 1-2, out 3-4 etc….
This done, everything should be just fine.
Good Luck and Best Vibes
ॐC☸Cॐ